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The eukaryotic CMG helicase at the replication fork: Emerging architecture reveals an unexpected mechanism
The eukaryotic helicase is an 11-subunit machine containing an Mcm2-7 motor ring that encircles DNA, Cdc45 and the GINS tetramer, referred to as CMG (Cdc45, Mcm2-7, GINS). CMG is “built” on DNA at origins in two steps. First, two Mcm2-7 rings are assembled around duplex DNA at origins in G1 phase, f...
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| 出版年: | Bioessays |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5873959/ https://ncbi.nlm.nih.gov/pubmed/29405332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201700208 |
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