Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation

The eukaryotic CMG (Cdc45, Mcm2–7, GINS) helicase consists of the Mcm2–7 hexameric ring along with five accessory factors. The Mcm2–7 heterohexamer, like other hexameric helicases, is shaped like a ring with two tiers, an N-tier ring composed of the N-terminal domains, and a C-tier of C-terminal dom...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Georgescu, Roxana, Yuan, Zuanning, Bai, Lin, de Luna Almeida Santos, Ruda, Sun, Jingchuan, Zhang, Dan, Yurieva, Olga, Li, Huilin, O’Donnell, Michael E.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293012/
https://ncbi.nlm.nih.gov/pubmed/28096349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620500114
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items