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Single-molecule analysis of the E. coli replisome and use of clamps to bypass replication barriers

The process of chromosome duplication faces many obstacles. One way to circumvent blocks is to hop over them by placing a new clamp on a downstream primer. This resembles lagging strand synthesis, where the tight grip of polymerase to the clamp and DNA must be overcome upon completing each Okazaki f...

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Bibliografiset tiedot
Päätekijät: Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Mike
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919775/
https://ncbi.nlm.nih.gov/pubmed/20388515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.003
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