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Single-molecule analysis of the E. coli replisome and use of clamps to bypass replication barriers
The process of chromosome duplication faces many obstacles. One way to circumvent blocks is to hop over them by placing a new clamp on a downstream primer. This resembles lagging strand synthesis, where the tight grip of polymerase to the clamp and DNA must be overcome upon completing each Okazaki f...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919775/ https://ncbi.nlm.nih.gov/pubmed/20388515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.003 |
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