Loading...

Single-molecule analysis of the E. coli replisome and use of clamps to bypass replication barriers

The process of chromosome duplication faces many obstacles. One way to circumvent blocks is to hop over them by placing a new clamp on a downstream primer. This resembles lagging strand synthesis, where the tight grip of polymerase to the clamp and DNA must be overcome upon completing each Okazaki f...

Full description

Saved in:
Bibliographic Details
Main Authors: Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Mike
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919775/
https://ncbi.nlm.nih.gov/pubmed/20388515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.003
Tags: Add Tag
No Tags, Be the first to tag this record!