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DNA Replication: How Does a Sliding Clamp Slide?

DNA sliding clamps are rings that tether certain enzymes to DNA. How clamp proteins slide on DNA has remained a mystery. A new crystal structure, together with molecular dynamics and NMR studies, has revealed how the human PCNA clamp slides on DNA.

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Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Yao, Nina Y., O’Donnell, Mike
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785930/
https://ncbi.nlm.nih.gov/pubmed/28267969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.01.053
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