STRUCTURE OF A SLIDING CLAMP ON DNA

The structure of the E. coli β-clamp polymerase processivity factor has been solved in complex with primed DNA. Interestingly, the clamp directly binds the DNA duplex, and also forms a crystal contact the ssDNA template strand which fits binds into the protein binding pocket of the clamp. We demonst...

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Bibliographic Details
Main Authors: Georgescu, Roxana E., Kim, Seung-Sup, Yurieva, Olga, Kuriyan, John, Kong, Xiang-Peng, O’Donnell, Mike
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443641/
https://ncbi.nlm.nih.gov/pubmed/18191219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.11.045
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