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Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium

BACKGROUND: Sliding DNA clamps are processivity factors that are required for efficient DNA replication. DNA polymerases maintain proximity to nucleic acid templates by interacting with sliding clamps that encircle DNA and thereby link the polymerase enzyme to the DNA substrate. Although the structu...

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Detalhes bibliográficos
Main Authors: Argiriadi, Maria A, Goedken, Eric R, Bruck, Irina, O'Donnell, Mike, Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368978/
https://ncbi.nlm.nih.gov/pubmed/16403212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-6-2
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