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Replisome mechanics: lagging strand events that influence speed and processivity

The antiparallel structure of DNA requires lagging strand synthesis to proceed in the opposite direction of the replication fork. This imposes unique events that occur only on the lagging strand, such as primase binding to DnaB helicase, RNA synthesis, and SS B antigen (SSB) displacement during Okaz...

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Bibliografiske detaljer
Main Authors: Georgescu, Roxana E., Yao, Nina, Indiani, Chiara, Yurieva, Olga, O'Donnell, Mike E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041431/
https://ncbi.nlm.nih.gov/pubmed/24829446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku257
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