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Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase
All cells contain specialized translesion DNA polymerases that replicate past sites of DNA damage. We find that Escherichia coli translesion DNA polymerase II (Pol II) and polymerase IV (Pol IV) function with DnaB helicase and regulate its rate of unwinding, slowing it to as little as 1 bp/s. Furthe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654394/ https://ncbi.nlm.nih.gov/pubmed/19279203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901403106 |
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