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RecA acts as a switch to regulate polymerase occupancy in a moving replication fork
This report discovers a role of Escherichia coli RecA, the cellular recombinase, in directing the action of several DNA polymerases at the replication fork. Bulk chromosome replication is performed by DNA polymerase (Pol) III. However, E. coli contains translesion synthesis (TLS) Pols II, IV, and V...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619308/ https://ncbi.nlm.nih.gov/pubmed/23509251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303301110 |
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