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RecA acts as a switch to regulate polymerase occupancy in a moving replication fork

This report discovers a role of Escherichia coli RecA, the cellular recombinase, in directing the action of several DNA polymerases at the replication fork. Bulk chromosome replication is performed by DNA polymerase (Pol) III. However, E. coli contains translesion synthesis (TLS) Pols II, IV, and V...

詳細記述

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書誌詳細
主要な著者: Indiani, Chiara, Patel, Meghna, Goodman, Myron F., O’Donnell, Mike E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619308/
https://ncbi.nlm.nih.gov/pubmed/23509251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303301110
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