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The active form of DNA polymerase V is UmuD′(2)C–RecA–ATP
DNA-damage-induced SOS mutations arise when Escherichia coli DNA polymerase (pol) V, activated by a RecA nucleoprotein filament (RecA*), catalyses translesion DNA synthesis. Here we address two longstanding enigmatic aspects of SOS mutagenesis, the molecular composition of mutagenically active pol V...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731490/ https://ncbi.nlm.nih.gov/pubmed/19606142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08178 |
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