A New Model for SOS-induced Mutagenesis: How RecA Protein Activates DNA Polymerase V

In Escherichia coli, cell survival and genomic stability after UV radiation depends on repair mechanisms induced as part of the SOS response to DNA damage. The early phase of the SOS response is mostly dominated by accurate DNA repair, while the later phase is characterized with elevated mutation le...

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Hauptverfasser: Patel, Meghna, Jiang, Qingfei, Woodgate, Roger, Cox, Michael M., Goodman, Myron F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874081/
https://ncbi.nlm.nih.gov/pubmed/20441441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2010.480968
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