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WHITHER THE REPLISOME: EMERGING PERSPECTIVES ON THE DYNAMIC NATURE OF THE DNA REPLICATION MACHINERY

Replisomes were originally thought to be multi-protein machines with a stabile and defined structure during replication. Discovery that replisomes repeatedly discard sliding clamps and assemble a new clamp to start each Okazaki fragment provided the first hint that the replisome structure changes du...

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Detalhes bibliográficos
Main Authors: Langston, Lance D., Indiani, Chiara, O’Donnell, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945305/
https://ncbi.nlm.nih.gov/pubmed/19652539
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