Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin

Por Parsons, Matthew P., Kang, Rujun, Buren, Caodu, Dau, Alejandro, Southwell, Amber L., Doty, Crystal N., Sanders, Shaun S., Hayden, Michael R., Raymond, Lynn A.
Publicado em 2014

Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes

Por Baine, Fiona K, Kay, Chris, Ketelaar, Maria E, Collins, Jennifer A, Semaka, Alicia, Doty, Crystal N, Krause, Amanda, Jacquie Greenberg, L, Hayden, Michael R
Publicado em 2013

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia

Por Warby, Simon C, Visscher, Henk, Collins, Jennifer A, Doty, Crystal N, Carter, Catherine, Butland, Stefanie L, Hayden, Anna R, Kanazawa, Ichiro, Ross, Colin J, Hayden, Michael R
Publicado em 2011

Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin

Por Carroll, Jeffrey B, Warby, Simon C, Southwell, Amber L, Doty, Crystal N, Greenlee, Sarah, Skotte, Niels, Hung, Gene, Bennett, C Frank, Freier, Susan M, Hayden, Michael R
Publicado em 2011

Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry

Por Kay, Chris, Collins, Jennifer A, Skotte, Niels H, Southwell, Amber L, Warby, Simon C, Caron, Nicholas S, Doty, Crystal N, Nguyen, Betty, Griguoli, Annamaria, Ross, Colin J, Squitieri, Ferdinando, Hayden, Michael R
Publicado no Mol Ther (2015)

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Por Østergaard, Michael E., Southwell, Amber L., Kordasiewicz, Holly, Watt, Andrew T., Skotte, Niels H., Doty, Crystal N., Vaid, Kuljeet, Villanueva, Erika B., Swayze, Eric E., Frank Bennett, C., Hayden, Michael R., Seth, Punit P.
Publicado em 2013

A fully humanized transgenic mouse model of Huntington disease

Por Southwell, Amber L., Warby, Simon C., Carroll, Jeffrey B., Doty, Crystal N., Skotte, Niels H., Zhang, Weining, Villanueva, Erika B., Kovalik, Vlad, Xie, Yuanyun, Pouladi, Mahmoud A., Collins, Jennifer A., Yang, X. William, Franciosi, Sonia, Hayden, Michael R.
Publicado em 2013

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity

Por Mattis, Virginia B., Tom, Colton, Akimov, Sergey, Saeedian, Jasmine, Østergaard, Michael E., Southwell, Amber L., Doty, Crystal N., Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Arjomand, Jamshid, Hayden, Michael R., Ross, Christopher A., Svendsen, Clive N.
Publicado no Hum Mol Genet (2015)

Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients

Por Skotte, Niels H., Southwell, Amber L., Østergaard, Michael E., Carroll, Jeffrey B., Warby, Simon C., Doty, Crystal N., Petoukhov, Eugenia, Vaid, Kuljeet, Kordasiewicz, Holly, Watt, Andrew T., Freier, Susan M., Hung, Gene, Seth, Punit P., Bennett, C. Frank, Swayze, Eric E., Hayden, Michael R.
Publicado em 2014

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Por Southwell, Amber L, Skotte, Niels H, Kordasiewicz, Holly B, Østergaard, Michael E, Watt, Andrew T, Carroll, Jeffrey B, Doty, Crystal N, Villanueva, Erika B, Petoukhov, Eugenia, Vaid, Kuljeet, Xie, Yuanyun, Freier, Susan M, Swayze, Eric E, Seth, Punit P, Bennett, Clarence Frank, Hayden, Michael R
Publicado no Mol Ther (2014)

Altered palmitoylation and neuropathological deficits in mice lacking HIP14

Por Singaraja, Roshni R., Huang, Kun, Sanders, Shaun S., Milnerwood, Austen J., Hines, Rochelle, Lerch, Jason P., Franciosi, Sonia, Drisdel, Renaldo C., Vaid, Kuljeet, Young, Fiona B., Doty, Crystal, Wan, Junmei, Bissada, Nagat, Henkelman, R. Mark, Green, William N., Davis, Nicholas G., Raymond, Lynn A., Hayden, Michael R.
Publicado em 2011