Identification of Binding Sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L

Por Sanders, Shaun S., Mui, Katherine K. N., Sutton, Liza M., Hayden, Michael R.
Publicado em 2014

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity

Por Huang, Kun, Sanders, Shaun, Singaraja, Roshni, Orban, Paul, Cijsouw, Tony, Arstikaitis, Pamela, Yanai, Anat, Hayden, Michael R., El-Husseini, Alaa
Publicado em 2009

Tracking Brain Palmitoylation Change: Predominance of Glial Change in a Mouse Model of Huntington Disease

Por Wan, Junmei, Savas, Jeffrey N., Roth, Amy F., Sanders, Shaun S., Singaraja, Roshni R., Hayden, Michael R., Yates, John R., Davis, Nicholas G.
Publicado em 2013

Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

Por Sanders, Shaun S., Martin, Dale D. O., Butland, Stefanie L., Lavallée-Adam, Mathieu, Calzolari, Diego, Kay, Chris, Yates, John R., Hayden, Michael R.
Publicado no PLoS Comput Biol (2015)

Palmitoylation of caspase-6 by HIP14 regulates its activation

Por Skotte, Niels H, Sanders, Shaun S, Singaraja, Roshni R, Ehrnhoefer, Dagmar E, Vaid, Kuljeet, Qiu, Xiaofan, Kannan, Srinivasaragavan, Verma, Chandra, Hayden, Michael R
Publicado no Cell Death Differ (2017)

Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin

Por Parsons, Matthew P., Kang, Rujun, Buren, Caodu, Dau, Alejandro, Southwell, Amber L., Doty, Crystal N., Sanders, Shaun S., Hayden, Michael R., Raymond, Lynn A.
Publicado em 2014

Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice

Por Sanders, Shaun S., Parsons, Matthew P., Mui, Katherine K. N., Southwell, Amber L., Franciosi, Sonia, Cheung, Daphne, Waltl, Sabine, Raymond, Lynn A., Hayden, Michael R.
Publicado no BMC Biol (2016)

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14

Por Huang, Kun, Sanders, Shaun S., Kang, Rujun, Carroll, Jeffrey B., Sutton, Liza, Wan, Junmei, Singaraja, Roshni, Young, Fiona B., Liu, Lili, El-Husseini, Alaa, Davis, Nicholas G., Hayden, Michael R.
Publicado em 2011

Low Levels of Human HIP14 Are Sufficient to Rescue Neuropathological, Behavioural, and Enzymatic Defects Due to Loss of Murine HIP14 in Hip14−/− Mice

Por Young, Fiona B., Franciosi, Sonia, Spreeuw, Amanda, Deng, Yu, Sanders, Shaun, Tam, Natalie C. M., Huang, Kun, Singaraja, Roshni R., Zhang, Weining, Bissada, Nagat, Kay, Chris, Hayden, Michael R.
Publicado em 2012

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease

Por Butland, Stefanie L., Sanders, Shaun S., Schmidt, Mandi E., Riechers, Sean-Patrick, Lin, David T.S., Martin, Dale D.O., Vaid, Kuljeet, Graham, Rona K., Singaraja, Roshni R., Wanker, Erich E., Conibear, Elizabeth, Hayden, Michael R.
Publicado em 2014

Altered palmitoylation and neuropathological deficits in mice lacking HIP14

Por Singaraja, Roshni R., Huang, Kun, Sanders, Shaun S., Milnerwood, Austen J., Hines, Rochelle, Lerch, Jason P., Franciosi, Sonia, Drisdel, Renaldo C., Vaid, Kuljeet, Young, Fiona B., Doty, Crystal, Wan, Junmei, Bissada, Nagat, Henkelman, R. Mark, Green, William N., Davis, Nicholas G., Raymond, Lynn A., Hayden, Michael R.
Publicado em 2011