Altered palmitoylation and neuropathological deficits in mice lacking HIP14

Huntingtin interacting protein 14 (HIP14, ZDHHC17) is a huntingtin (HTT) interacting protein with palmitoyl transferase activity. In order to interrogate the function of Hip14, we generated mice with disruption in their Hip14 gene. Hip14−/− mice displayed behavioral, biochemical and neuropathologica...

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Detalhes bibliográficos
Main Authors: Singaraja, Roshni R., Huang, Kun, Sanders, Shaun S., Milnerwood, Austen J., Hines, Rochelle, Lerch, Jason P., Franciosi, Sonia, Drisdel, Renaldo C., Vaid, Kuljeet, Young, Fiona B., Doty, Crystal, Wan, Junmei, Bissada, Nagat, Henkelman, R. Mark, Green, William N., Davis, Nicholas G., Raymond, Lynn A., Hayden, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177655/
https://ncbi.nlm.nih.gov/pubmed/21775500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr308
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