Palmitoylation of caspase-6 by HIP14 regulates its activation

Caspase-6 (CASP6) has an important role in axonal degeneration during neuronal apoptosis and in the neurodegenerative diseases Alzheimer and Huntington disease. Decreasing CASP6 activity may help to restore neuronal function in these and other diseases such as stroke and ischemia, where increased CA...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Skotte, Niels H, Sanders, Shaun S, Singaraja, Roshni R, Ehrnhoefer, Dagmar E, Vaid, Kuljeet, Qiu, Xiaofan, Kannan, Srinivasaragavan, Verma, Chandra, Hayden, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344205/
https://ncbi.nlm.nih.gov/pubmed/27911442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.139
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