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Tracking Brain Palmitoylation Change: Predominance of Glial Change in a Mouse Model of Huntington Disease

Protein palmitoylation, a reversible lipid modification of proteins, is widely used in the nervous system, with dysregulated palmitoylation being implicated in a variety of neurological disorders. Described below is ABE/SILAM, a new proteomic strategy that couples acyl-biotinyl exchange (ABE) purifi...

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Detalhes bibliográficos
Main Authors: Wan, Junmei, Savas, Jeffrey N., Roth, Amy F., Sanders, Shaun S., Singaraja, Roshni R., Hayden, Michael R., Yates, John R., Davis, Nicholas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880188/
https://ncbi.nlm.nih.gov/pubmed/24211138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.09.018
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