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Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes

Huntington disease (HD) is a neurodegenerative disorder resulting from the expansion of a CAG trinucleotide repeat in the huntingtin (HTT) gene. Worldwide prevalence varies geographically with the highest figures reported in populations of European ancestry. HD in South Africa has been reported in C...

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Detalhes bibliográficos
Main Authors: Baine, Fiona K, Kay, Chris, Ketelaar, Maria E, Collins, Jennifer A, Semaka, Alicia, Doty, Crystal N, Krause, Amanda, Jacquie Greenberg, L, Hayden, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778359/
https://ncbi.nlm.nih.gov/pubmed/23463025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.2
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