Geranylgeranyltransferase I as a target for anti-cancer drugs

od Philips, Mark R., Cox, Adrienne D.
Izdano 2007

Ras history: The saga continues

od Cox, Adrienne D, Der, Channing J
Izdano 2010

The RAF Inhibitor Paradox Revisited

od Cox, Adrienne D., Der, Channing J.
Izdano 2012

The role of wild type RAS isoforms in cancer

od Zhou, Bingying, Der, Channing J., Cox, Adrienne D.
Izdano u Semin Cell Dev Biol (2016)

Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

od Cox, Adrienne D., Der, Channing J., Philips, Mark R.
Izdano u Clin Cancer Res (2015)

Single Cell Ras-GTP Analysis Reveals Altered Ras Activity in a Subpopulation of Neurofibroma Schwann Cells but Not Fibroblasts

od Sherman, Larry S., Atit, Radhika, Rosenbaum, Thorsten, Cox, Adrienne D., Ratner, Nancy
Izdano 2000

Rho GTPases, oxidation, and cell redox control

od Hobbs, G Aaron, Zhou, Bingying, Cox, Adrienne D, Campbell, Sharon L
Izdano 2014

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

od Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Izdano 1999

Targeting RAS-mutant cancers: is ERK the key?

od Ryan, Meagan B., Der, Channing J., Wang-Gillam, Andrea, Cox, Adrienne D.
Izdano u Trends Cancer (2015)

The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

od Brady, Donita C., Alan, Jamie K., Madigan, James P., Fanning, Alan S., Cox, Adrienne D.
Izdano 2009

Phosphorylation by Protein Kinase Cα Regulates RalB Small GTPase Protein Activation, Subcellular Localization, and Effector Utilization

od Martin, Timothy D., Mitin, Natalia, Cox, Adrienne D., Yeh, Jen Jen, Der, Channing J.
Izdano 2012

Drugging the undruggable Ras: mission possible?

od Cox, Adrienne D., Fesik, Stephen W., Kimmelman, Alec C., Luo, Ji, Der, Channing J.
Izdano u Nat Rev Drug Discov (2014)

Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ER...

od Zhou, Bingying, Ritt, Daniel A., Morrison, Deborah K., Der, Channing J., Cox, Adrienne D.
Izdano u J Biol Chem (2016)

Regulation of the Rho Family Small GTPase Wrch-1/RhoU by C-Terminal Tyrosine Phosphorylation Requires Src

od Alan, Jamie K., Berzat, Anastacia C., Dewar, Brian J., Graves, Lee M., Cox, Adrienne D.
Izdano 2010

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion

od Fiordalisi, James J., Dewar, Brian J., Graves, Lee M., Madigan, James P., Cox, Adrienne D.
Izdano 2013

The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

od Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Izdano u PLoS One (2015)

Differential Requirement of CAAX-mediated Posttranslational Processing for Rheb Localization and Signaling

od Hanker, Ariella B., Mitin, Natalia, Wilder, Rhonda S., Henske, Elizabeth Petri, Tamanoi, Fuyuhiko, Cox, Adrienne D., Der, Channing J.
Izdano 2009

Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells

od Huang, Yuan, Rangwala, Fatima, Fulkerson, Patricia C, Ling, Bo, Reed, Erin, Cox, Adrienne D, Kamholz, John, Ratner, Nancy
Izdano 2004

The Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation

od Kidd, Ambrose R., Snider, Jared L., Martin, Timothy D., Graboski, Sarah F., Der, Channing J., Cox, Adrienne D.
Izdano 2010

TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling

od Campbell, Paul M, Boufaied, Nadia, Fiordalisi, James J, Cox, Adrienne D, Falardeau, Pierre, Der, Channing J, Gourdeau, Henriette
Izdano 2010