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Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells

The neurofibromatosis type 1 tumor suppressor protein neurofibromin, is a GTPase activating protein for H-, N-, K-, R-Ras and TC21/R-Ras2 proteins. We demonstrate that Schwann cells derived from Nf1-null mice have enhanced chemokinetic and chemotactic migration in comparison to wild-type controls. S...

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Autores principales: Huang, Yuan, Rangwala, Fatima, Fulkerson, Patricia C, Ling, Bo, Reed, Erin, Cox, Adrienne D, Kamholz, John, Ratner, Nancy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854497/
https://ncbi.nlm.nih.gov/pubmed/14724565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207075
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