Geranylgeranyltransferase I as a target for anti-cancer drugs

door Philips, Mark R., Cox, Adrienne D.
Gepubliceerd in 2007

Ras history: The saga continues

door Cox, Adrienne D, Der, Channing J
Gepubliceerd in 2010

The RAF Inhibitor Paradox Revisited

door Cox, Adrienne D., Der, Channing J.
Gepubliceerd in 2012

The role of wild type RAS isoforms in cancer

door Zhou, Bingying, Der, Channing J., Cox, Adrienne D.
Gepubliceerd in Semin Cell Dev Biol (2016)

Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

door Cox, Adrienne D., Der, Channing J., Philips, Mark R.
Gepubliceerd in Clin Cancer Res (2015)

Single Cell Ras-GTP Analysis Reveals Altered Ras Activity in a Subpopulation of Neurofibroma Schwann Cells but Not Fibroblasts

door Sherman, Larry S., Atit, Radhika, Rosenbaum, Thorsten, Cox, Adrienne D., Ratner, Nancy
Gepubliceerd in 2000

Rho GTPases, oxidation, and cell redox control

door Hobbs, G Aaron, Zhou, Bingying, Cox, Adrienne D, Campbell, Sharon L
Gepubliceerd in 2014

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

door Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Gepubliceerd in 1999

Targeting RAS-mutant cancers: is ERK the key?

door Ryan, Meagan B., Der, Channing J., Wang-Gillam, Andrea, Cox, Adrienne D.
Gepubliceerd in Trends Cancer (2015)

The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

door Brady, Donita C., Alan, Jamie K., Madigan, James P., Fanning, Alan S., Cox, Adrienne D.
Gepubliceerd in 2009

Phosphorylation by Protein Kinase Cα Regulates RalB Small GTPase Protein Activation, Subcellular Localization, and Effector Utilization

door Martin, Timothy D., Mitin, Natalia, Cox, Adrienne D., Yeh, Jen Jen, Der, Channing J.
Gepubliceerd in 2012

Drugging the undruggable Ras: mission possible?

door Cox, Adrienne D., Fesik, Stephen W., Kimmelman, Alec C., Luo, Ji, Der, Channing J.
Gepubliceerd in Nat Rev Drug Discov (2014)

Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ER...

door Zhou, Bingying, Ritt, Daniel A., Morrison, Deborah K., Der, Channing J., Cox, Adrienne D.
Gepubliceerd in J Biol Chem (2016)

Regulation of the Rho Family Small GTPase Wrch-1/RhoU by C-Terminal Tyrosine Phosphorylation Requires Src

door Alan, Jamie K., Berzat, Anastacia C., Dewar, Brian J., Graves, Lee M., Cox, Adrienne D.
Gepubliceerd in 2010

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion

door Fiordalisi, James J., Dewar, Brian J., Graves, Lee M., Madigan, James P., Cox, Adrienne D.
Gepubliceerd in 2013

The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

door Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Gepubliceerd in PLoS One (2015)

Differential Requirement of CAAX-mediated Posttranslational Processing for Rheb Localization and Signaling

door Hanker, Ariella B., Mitin, Natalia, Wilder, Rhonda S., Henske, Elizabeth Petri, Tamanoi, Fuyuhiko, Cox, Adrienne D., Der, Channing J.
Gepubliceerd in 2009

Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells

door Huang, Yuan, Rangwala, Fatima, Fulkerson, Patricia C, Ling, Bo, Reed, Erin, Cox, Adrienne D, Kamholz, John, Ratner, Nancy
Gepubliceerd in 2004

The Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation

door Kidd, Ambrose R., Snider, Jared L., Martin, Timothy D., Graboski, Sarah F., Der, Channing J., Cox, Adrienne D.
Gepubliceerd in 2010

TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling

door Campbell, Paul M, Boufaied, Nadia, Fiordalisi, James J, Cox, Adrienne D, Falardeau, Pierre, Der, Channing J, Gourdeau, Henriette
Gepubliceerd in 2010