Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion

Por Keely, Patricia J.
Publicado em 2011

Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression

Por Schedin, Pepper, Keely, Patricia J.
Publicado em 2011

Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition

Por Curran, Colleen S., Keely, Patricia J
Publicado em 2012

Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells

Por Wozniak, Michele A., Keely, Patricia J.
Publicado em 2005

The role of focal adhesion kinase in tumor initiation and progression

Por Provenzano, Paolo P, Keely, Patricia J
Publicado em 2009

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

Por Provenzano, Paolo P., Keely, Patricia J.
Publicado em 2011

Why the stroma matters in breast cancer: Insights into breast cancer patient outcomes through the examination of stromal biomarkers

Por Conklin, Matthew W., Keely, Patricia J.
Publicado em 2012

Rho family GTPases: making it to the third dimension

Por Riching, Kristin M., Keely, Patricia J.
Publicado no Int J Biochem Cell Biol (2014)

Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'.

Por Gabarra-Niecko, Veronica, Keely, Patricia J, Schaller, Michael D
Publicado em 2002

Shining new light on 3D cell motility and the metastatic process

Por Provenzano, Paolo P., Eliceiri, Kevin W., Keely, Patricia J.
Publicado em 2009

Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells

Por Curran, Colleen S., Carrillo, Esteban R., Ponik, Suzanne M., Keely, Patricia J.
Publicado no Environ Toxicol Pharmacol (2014)

Bi-directional signaling: Extracellular Matrix and Integrin Regulation of Breast Tumor Progression

Por Gehler, Scott, Ponik, Suzanne M., Riching, Kristin M, Keely, Patricia J.
Publicado no Crit Rev Eukaryot Gene Expr (2013)

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

Por Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Publicado em 1999

Matrix density-induced mechanoregulation of breast cell phenotype, signaling, and gene expression through a FAK-ERK linkage

Por Provenzano, Paolo P., Inman, David R., Eliceiri, Kevin W., Keely, Patricia J.
Publicado em 2009

Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells

Por Barcus, Craig E., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Publicado em 2013

Engineering three-dimensional collagen matrices to provide contact guidance during 3D cell migration

Por Provenzano, Paolo P., Eliceiri, Kevin W., Inman, David R., Keely, Patricia J.
Publicado em 2010

Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells

Por Barcus, Craig E., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Publicado no Oncotarget (2016)

R-Ras Promotes Focal Adhesion Formation through Focal Adhesion Kinase and p130(Cas) by a Novel Mechanism That Differs from Integrins

Por Kwong, Lina, Wozniak, Michele A., Collins, Asha S., Wilson, Siobhan D., Keely, Patricia J.
Publicado em 2003

R-Ras Controls Membrane Protrusion and Cell Migration through the Spatial Regulation of Rac and Rho

Por Wozniak, Michele A., Kwong, Lina, Chodniewicz, David, Klemke, Richard L., Keely, Patricia J.
Publicado em 2005

RhoA Biological Activity Is Dependent on Prenylation but Independent of Specific Isoprenoid Modification()

Por Solski, Patricia A., Helms, Whitney, Keely, Patricia J., Su, Lishan, Der, Channing J.
Publicado no Cell Growth Differ (2002)