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Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells

Clinically, circulating prolactin levels and density of the extracellular matrix (ECM) are individual risk factors for breast cancer. As tumors develop, the surrounding stroma responds with increased deposition and cross-linking of the collagen matrix (desmoplasia). In mouse models, prolactin promot...

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Bibliografische gegevens
Hoofdauteurs: Barcus, Craig E., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642318/
https://ncbi.nlm.nih.gov/pubmed/23530035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447631
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