Ovarian stiffness increases with age in the mammalian ovary and depends on collagen and hyaluronan matrices

Fibrosis is a hallmark of aging tissues which often leads to altered architecture and function. The ovary is the first organ to show overt signs of aging, including increased fibrosis in the ovarian stroma. How this fibrosis affects ovarian biomechanics and the underlying mechanisms are unknown. Usi...

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Vydáno v:Aging Cell
Hlavní autoři: Amargant, Farners, Manuel, Sharrón L., Tu, Qing, Parkes, Wendena S., Rivas, Felipe, Zhou, Luhan T., Rowley, Jennifer E., Villanueva, Cecilia E., Hornick, Jessica E., Shekhawat, Gajendra S., Wei, Jian‐Jun, Pavone, Mary Ellen, Hall, Adam R., Pritchard, Michele T., Duncan, Francesca E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681059/
https://ncbi.nlm.nih.gov/pubmed/33079460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13259
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