Ovarian stiffness increases with age in the mammalian ovary and depends on collagen and hyaluronan matrices

Fibrosis is a hallmark of aging tissues which often leads to altered architecture and function. The ovary is the first organ to show overt signs of aging, including increased fibrosis in the ovarian stroma. How this fibrosis affects ovarian biomechanics and the underlying mechanisms are unknown. Usi...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Amargant, Farners, Manuel, Sharrón L., Tu, Qing, Parkes, Wendena S., Rivas, Felipe, Zhou, Luhan T., Rowley, Jennifer E., Villanueva, Cecilia E., Hornick, Jessica E., Shekhawat, Gajendra S., Wei, Jian‐Jun, Pavone, Mary Ellen, Hall, Adam R., Pritchard, Michele T., Duncan, Francesca E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681059/
https://ncbi.nlm.nih.gov/pubmed/33079460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13259
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