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Matrix Remodeling and Hyaluronan Production by Myofibroblasts and Cancer-Associated Fibroblasts in 3D Collagen Matrices

The tumor microenvironment is a key modulator in cancer progression and has become a novel target in cancer therapy. An increase in hyaluronan (HA) accumulation and metabolism can be found in advancing tumor progression and are often associated with aggressive malignancy, drug resistance and poor pr...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gels
Auteurs principaux: Sapudom, Jiranuwat, Müller, Claudia Damaris, Nguyen, Khiet-Tam, Martin, Steve, Anderegg, Ulf, Pompe, Tilo
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709683/
https://ncbi.nlm.nih.gov/pubmed/33008082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/gels6040033
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