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Matrix Remodeling and Hyaluronan Production by Myofibroblasts and Cancer-Associated Fibroblasts in 3D Collagen Matrices

The tumor microenvironment is a key modulator in cancer progression and has become a novel target in cancer therapy. An increase in hyaluronan (HA) accumulation and metabolism can be found in advancing tumor progression and are often associated with aggressive malignancy, drug resistance and poor pr...

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Detalhes bibliográficos
Publicado no:Gels
Main Authors: Sapudom, Jiranuwat, Müller, Claudia Damaris, Nguyen, Khiet-Tam, Martin, Steve, Anderegg, Ulf, Pompe, Tilo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709683/
https://ncbi.nlm.nih.gov/pubmed/33008082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/gels6040033
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