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Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells
Breast density, where collagen I is the dominant component, is a significant breast cancer risk factor. Cell surface integrins interact with collagen, activate focal adhesion kinase (FAK), and downstream cell signals associated with xenobiotics (AhR, ARNT) and hypoxia (HIF-1α, ARNT). We examined if...
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| I publikationen: | Environ Toxicol Pharmacol |
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| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323890/ https://ncbi.nlm.nih.gov/pubmed/25481308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.etap.2014.10.017 |
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