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ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

Breast epithelial cells differentiate into tubules when cultured in floating three-dimensional (3D) collagen gels, but not when the cells are cultured in the same collagen matrix that is attached to the culture dish. These observations suggest that the biophysical properties of collagenous matrices...

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Detalhes bibliográficos
Main Authors: Wozniak, Michele A., Desai, Radhika, Solski, Patricia A., Der, Channing J., Keely, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173660/
https://ncbi.nlm.nih.gov/pubmed/14610060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305010
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