Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment

BACKGROUND: High mammographic density has been correlated with a 4-fold to 6-fold increased risk of developing breast cancer, and is associated with increased stromal deposition of extracellular matrix proteins, including collagen I. The molecular and cellular mechanisms responsible for high breast...

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Udgivet i:Breast Cancer Res
Main Authors: García-Mendoza, María G., Inman, David R., Ponik, Suzanne M., Jeffery, Justin J., Sheerar, Dagna S., Van Doorn, Rachel R., Keely, Patricia J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864897/
https://ncbi.nlm.nih.gov/pubmed/27169366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0703-7
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