Biophysical and Proteomic Characterization Strategies for Cysteine Modifications in Ras GTPases

Por Hobbs, G. Aaron, Gunawardena, Harsha P., Campbell, Sharon L.
Publicado em 2014

RAS isoforms and mutations in cancer at a glance

Por Hobbs, G. Aaron, Der, Channing J., Rossman, Kent L.
Publicado no J Cell Sci (2016)

Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy

Por Bhaskar, Kiran, Hobbs, G. Aaron, Yen, Shu-Hui, Lee, Gloria
Publicado em 2010

Redox Regulation of Ras and Rho GTPases: Mechanism and Function

Por Mitchell, Lauren, Hobbs, G. Aaron, Aghajanian, Amir, Campbell, Sharon L.
Publicado em 2013

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

Por Hobbs, G Aaron, Gunawardena, Harsha P, Baker, Rachael, Campbell, Sharon L
Publicado em 2013

Rho GTPases, oxidation, and cell redox control

Por Hobbs, G Aaron, Zhou, Bingying, Cox, Adrienne D, Campbell, Sharon L
Publicado em 2014

Glutathiolated Ras: Characterization and Implications for Ras Activation

Por Hobbs, G. Aaron, Bonini, Marcelo G., Gunawardena, Harsha P., Chen, Xian, Campbell, Sharon L.
Publicado em 2012

Redox regulation of Rac1 by thiol oxidation

Por Hobbs, G. Aaron, Mitchell, Lauren E., Arrington, Megan E., Gunawardena, Harsha P., DeCristo, Molly J., Loeser, Richard F., Chen, Xian, Cox, Adrienne D., Campbell, Sharon L.
Publicado no Free Radic Biol Med (2014)

Copper is required for oncogenic BRAF signaling and tumorigenesis

Por Brady, Donita C., Crowe, Matthew S., Turski, Michelle L., Hobbs, G. Aaron, Yao, Xiaojie, Chaikuad, Apirat, Knapp, Stefan, Xiao, Kunhong, Campbell, Sharon L., Thiele, Dennis J., Counter, Christopher M.
Publicado em 2014

Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies

Por Waters, Andrew M., Ozkan-Dagliyan, Irem, Vaseva, Angelina V., Fer, Nicole, Strathern, Leslie A., Hobbs, G. Aaron, Tessier-Cloutier, Basile, Gillette, William K., Bagni, Rachel, Whiteley, Gordon R., Hartley, James L., McCormick, Frank, Cox, Adrienne D., Houghton, Peter J., Huntsman, David G., Philips, Mark R., Der, Channing J.
Publicado no Sci Signal (2017)

Atypical KRAS(G12R) Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

Por Hobbs, G. Aaron, Baker, Nicole M., Miermont, Anne M., Thurman, Ryan D., Pierobon, Mariaelena, Tran, Timothy H., Anderson, Andrew O., Waters, Andrew M., Diehl, J. Nathaniel, Papke, Bjoern, Hodge, Richard G., Klomp, Jennifer E., Goodwin, Craig M., DeLiberty, Jonathan M., Wang, Junning, Ng, Raymond W. S., Gautam, Prson, Bryant, Kirsten L., Esposito, Dominic, Campbell, Sharon L., Petricoin, Emanuel F., Simanshu, Dhirendra K., Aguirre, Andrew J., Wolpin, Brian M., Wennerberg, Krister, Rudloff, Udo, Cox, Adrienne D., Der, Channing J.
Publicado no Cancer Discov (2019)

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Por Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.
Publicado no Nat Med (2019)