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Biophysical and Proteomic Characterization Strategies for Cysteine Modifications in Ras GTPases

Cysteine is one of the most reactive amino acids and is modified by a number of oxidants. The reactivity of cysteines is dependent on the thiol pK(a); however, measuring cysteine pK(a) values is nontrivial. Ras family GTPases have been shown to contain a free cysteine that is sensitive to oxidation,...

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Détails bibliographiques
Auteurs principaux: Hobbs, G. Aaron, Gunawardena, Harsha P., Campbell, Sharon L.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067004/
https://ncbi.nlm.nih.gov/pubmed/24470020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-791-4_6
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