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Biophysical and Proteomic Characterization Strategies for Cysteine Modifications in Ras GTPases
Cysteine is one of the most reactive amino acids and is modified by a number of oxidants. The reactivity of cysteines is dependent on the thiol pK(a); however, measuring cysteine pK(a) values is nontrivial. Ras family GTPases have been shown to contain a free cysteine that is sensitive to oxidation,...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067004/ https://ncbi.nlm.nih.gov/pubmed/24470020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-791-4_6 |
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