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The Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation
PURPOSE: Oncogenic activation of Ras renders cancer cells resistant to ionizing radiation (IR), but the mechanisms have not been fully characterized. The Ras-like small GTPases, RalA and RalB, are downstream effectors of Ras function and are critical for both tumor growth and survival. The Ral effec...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922474/ https://ncbi.nlm.nih.gov/pubmed/20619549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.03.023 |
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