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Differential involvement of RalA and RalB in colorectal cancer

Mutationally activated K-Ras can utilize a multitude of downstream effector proteins to promote oncogenesis. While the Raf and phosphoinositol 3-kinase effector pathways are the best-studied and validated, recent studies have established the critical importance of Ral guanine nucleotide exchange fac...

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Detalhes bibliográficos
Main Authors: Martin, Timothy D., Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408977/
https://ncbi.nlm.nih.gov/pubmed/22790202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.19571
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