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Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA
The small GTPase Ras, which transmits extracellular signals to the cell, and the kinase Aurora-A, which promotes proper mitosis, can both be inappropriately activated in human tumors. Here, we show that Aurora-A in conjunction with oncogenic Ras enhances transformed cell growth. Furthermore, such tr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798468/ https://ncbi.nlm.nih.gov/pubmed/19901077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00916-08 |
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