RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation

Healthy mitochondria use an electrochemical gradient across the inner mitochondrial membrane (IMM) to generate energy in the form of ATP. A variety of endogenous and exogenous factors can lead to transient or sustained depolarization of the IMM, including mitochondrial fission events, expression of...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pollock, Sarah R., Schinlever, Austin R., Rohani, Ali, Kashatus, Jennifer A., Kashatus, David F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469766/
https://ncbi.nlm.nih.gov/pubmed/30995277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214764
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