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Breaking up is hard to do: RalA, mitochondrial fission and cancer

The small GTPases RalA and RalB are activated downstream of oncogenic Ras. While activation of RalA is critically important for tumor initiation and growth of Ras-driven cancers, the highly similar small GTPase RalB is implicated in cell survival and metastasis. This difference in function between t...

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Detalhes bibliográficos
Main Authors: Kashatus, David F., Counter, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337163/
https://ncbi.nlm.nih.gov/pubmed/22545232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.18284
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