Geranylgeranyltransferase I as a target for anti-cancer drugs

gan Philips, Mark R., Cox, Adrienne D.
Cyhoeddwyd 2007

Ras history: The saga continues

gan Cox, Adrienne D, Der, Channing J
Cyhoeddwyd 2010

The RAF Inhibitor Paradox Revisited

gan Cox, Adrienne D., Der, Channing J.
Cyhoeddwyd 2012

The role of wild type RAS isoforms in cancer

gan Zhou, Bingying, Der, Channing J., Cox, Adrienne D.
Cyhoeddwyd yn Semin Cell Dev Biol (2016)

Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

gan Cox, Adrienne D., Der, Channing J., Philips, Mark R.
Cyhoeddwyd yn Clin Cancer Res (2015)

Single Cell Ras-GTP Analysis Reveals Altered Ras Activity in a Subpopulation of Neurofibroma Schwann Cells but Not Fibroblasts

gan Sherman, Larry S., Atit, Radhika, Rosenbaum, Thorsten, Cox, Adrienne D., Ratner, Nancy
Cyhoeddwyd 2000

Rho GTPases, oxidation, and cell redox control

gan Hobbs, G Aaron, Zhou, Bingying, Cox, Adrienne D, Campbell, Sharon L
Cyhoeddwyd 2014

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

gan Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Cyhoeddwyd 1999

Targeting RAS-mutant cancers: is ERK the key?

gan Ryan, Meagan B., Der, Channing J., Wang-Gillam, Andrea, Cox, Adrienne D.
Cyhoeddwyd yn Trends Cancer (2015)

The Transforming Rho Family GTPase Wrch-1 Disrupts Epithelial Cell Tight Junctions and Epithelial Morphogenesis

gan Brady, Donita C., Alan, Jamie K., Madigan, James P., Fanning, Alan S., Cox, Adrienne D.
Cyhoeddwyd 2009

Phosphorylation by Protein Kinase Cα Regulates RalB Small GTPase Protein Activation, Subcellular Localization, and Effector Utilization

gan Martin, Timothy D., Mitin, Natalia, Cox, Adrienne D., Yeh, Jen Jen, Der, Channing J.
Cyhoeddwyd 2012

Drugging the undruggable Ras: mission possible?

gan Cox, Adrienne D., Fesik, Stephen W., Kimmelman, Alec C., Luo, Ji, Der, Channing J.
Cyhoeddwyd yn Nat Rev Drug Discov (2014)

Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ER...

gan Zhou, Bingying, Ritt, Daniel A., Morrison, Deborah K., Der, Channing J., Cox, Adrienne D.
Cyhoeddwyd yn J Biol Chem (2016)

Regulation of the Rho Family Small GTPase Wrch-1/RhoU by C-Terminal Tyrosine Phosphorylation Requires Src

gan Alan, Jamie K., Berzat, Anastacia C., Dewar, Brian J., Graves, Lee M., Cox, Adrienne D.
Cyhoeddwyd 2010

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion

gan Fiordalisi, James J., Dewar, Brian J., Graves, Lee M., Madigan, James P., Cox, Adrienne D.
Cyhoeddwyd 2013

The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

gan Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Cyhoeddwyd yn PLoS One (2015)

Differential Requirement of CAAX-mediated Posttranslational Processing for Rheb Localization and Signaling

gan Hanker, Ariella B., Mitin, Natalia, Wilder, Rhonda S., Henske, Elizabeth Petri, Tamanoi, Fuyuhiko, Cox, Adrienne D., Der, Channing J.
Cyhoeddwyd 2009

Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells

gan Huang, Yuan, Rangwala, Fatima, Fulkerson, Patricia C, Ling, Bo, Reed, Erin, Cox, Adrienne D, Kamholz, John, Ratner, Nancy
Cyhoeddwyd 2004

The Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation

gan Kidd, Ambrose R., Snider, Jared L., Martin, Timothy D., Graboski, Sarah F., Der, Channing J., Cox, Adrienne D.
Cyhoeddwyd 2010

TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling

gan Campbell, Paul M, Boufaied, Nadia, Fiordalisi, James J, Cox, Adrienne D, Falardeau, Pierre, Der, Channing J, Gourdeau, Henriette
Cyhoeddwyd 2010