Cannabinoid receptor expression in non-small cell lung cancer. Effectiveness of tetrahydrocannabinol and cannabidiol inhibiting cell proliferation and epithelial-mesenchymal transi...

door Milian, Lara, Mata, Manuel, Alcacer, Javier, Oliver, María, Sancho-Tello, María, Martín de Llano, José Javier, Camps, Carlos, Galbis, José, Carretero, Julian, Carda, Carmen
Gepubliceerd in PLoS One (2020)

Loss of p53 Attenuates the Contribution of IL-6 Deletion on Suppressed Tumor Progression and Extended Survival in Kras-Driven Murine Lung Cancer

door Tan, Xiaohong, Carretero, Julian, Chen, Zhao, Zhang, Jishuai, Wang, Yanxiao, Chen, Jicheng, Li, Xiubin, Ye, Hui, Tang, Chuanhao, Cheng, Xuan, Hou, Ning, Yang, Xiao, Wong, Kwok-Kin
Gepubliceerd in 2013

Srebf2 Locus Overexpression Reduces Body Weight, Total Cholesterol and Glucose Levels in Mice Fed with Two Different Diets

door Andrés-Blasco, Irene, Blesa, Sebastian, Vinué, Ángela, González-Navarro, Herminia, Real, José Tomás, Martínez-Hervás, Sergio, Carretero, Julián, Ferrández-Izquierdo, Antonio, Chaves, Felipe Javier, García-García, Ana-Bárbara
Gepubliceerd in Nutrients (2020)

β-catenin contributes to lung tumor development induced by EGFR mutations

door Nakayama, Sohei, Sng, Natasha, Carretero, Julian, Welner, Robert, Hayashi, Yuichiro, Yamamoto, Mihoko, Tan, Alistair J., Yamaguchi, Norihiro, Yasuda, Hiroyuki, Li, Danan, Soejima, Kenzo, Soo, Ross A., Costa, Daniel B., Wong, Kwok-Kin, Kobayashi, Susumu S.
Gepubliceerd in 2014

PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion

door Bonastre, Ester, Verdura, Sara, Zondervan, Ilse, Facchinetti, Federica, Lantuejoul, Sylvie, Chiara, Maria Dolores, Rodrigo, Juan Pablo, Carretero, Julian, Condom, Enric, Vidal, Agustin, Sidransky, David, Villanueva, Alberto, Roz, Luca, Brambilla, Elisabeth, Savola, Suvi, Sanchez-Cespedes, Montse
Gepubliceerd in Cancer Res (2015)

Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer

door Shimamura, Takeshi, Chen, Zhao, Soucheray, Margaret, Carretero, Julian, Kikuchi, Eiki, Tchaicha, Jeremy H., Gao, Yandi, Cheng, Katherine A., Cohoon, Travis J., Qi, Jun, Akbay, Esra, Kimmelman, Alec C., Kung, Andrew L., Bradner, James E., Wong, Kwok-Kin
Gepubliceerd in 2013

Intratumoral heterogeneity in EGFR mutant NSCLC results in divergent resistance mechanisms in response to EGFR tyrosine kinase inhibition

door Soucheray, Margaret, Capelletti, Marzia, Pulido, Inés, Kuang, Yanan, Paweletz, Cloud P., Becker, Jeffrey H., Kikuchi, Eiki, Xu, Chunxiao, Patel, Tarun B., Al-shahrour, Fatima, Carretero, Julián, Wong, Kwok-Kin, Jänne, Pasi A., Shapiro, Geoffrey I., Shimamura, Takeshi
Gepubliceerd in Cancer Res (2015)

PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data

door Piñeiro-Yáñez, Elena, Reboiro-Jato, Miguel, Gómez-López, Gonzalo, Perales-Patón, Javier, Troulé, Kevin, Rodríguez, José Manuel, Tejero, Héctor, Shimamura, Takeshi, López-Casas, Pedro Pablo, Carretero, Julián, Valencia, Alfonso, Hidalgo, Manuel, Glez-Peña, Daniel, Al-Shahrour, Fátima
Gepubliceerd in Genome Med (2018)

Expression inactivation of SMARCA4 by microRNAs in lung tumors

door Coira, Isabel F., Rufino-Palomares, Eva E., Romero, Octavio A., Peinado, Paola, Metheetrairut, Chanatip, Boyero-Corral, Laura, Carretero, Julian, Farez-Vidal, Esther, Cuadros, Marta, Reyes-Zurita, Fernando J., Lupiáñez, Jose A., Sánchez-Cespedes, Montse, Slack, Frank J., Medina, Pedro P.
Gepubliceerd in Hum Mol Genet (2015)

Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response

door Weaver, Zoë, Difilippantonio, Simone, Carretero, Julian, Martin, Philip L., El Meskini, Rajaa, Iacovelli, Anthony J., Gumprecht, Michelle, Kulaga, Alan, Guerin, Theresa, Schlomer, Jerome, Baran, Maureen, Kozlov, Serguei, McCann, Thomas, Mena, Salvador, Al-Shahrour, Fatima, Alexander, Danny, Wong, Kwok-Kin, Van Dyke, Terry
Gepubliceerd in 2012

Ganetespib (STA-9090), a Non-Geldanamycin HSP90 Inhibitor, has Potent Antitumor Activity in In Vitro and In Vivo Models of Non-Small Cell Lung Cancer

door Shimamura, Takeshi, Perera, Samanthi A., Foley, Kevin P., Sang, Jim, Rodig, Scott J., Inoue, Takayo, Chen, Liang, Li, Danan, Carretero, Julian, Li, Yu-Chen, Sinha, Papiya, Carey, Christopher D., Borgman, Christa L., Jimenez, John-Paul, Meyerson, Matthew, Ying, Weiwen, Barsoum, James, Wong, Kwok-Kin, Shapiro, Geoffrey I.
Gepubliceerd in 2012

Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models

door Peinado, Paola, Andrades, Alvaro, Cuadros, Marta, Rodriguez, Maria Isabel, Coira, Isabel F., Garcia, Daniel J., Álvarez-Perez, Juan Carlos, Baliñas-Gavira, Carlos, Arenas, Alberto M., Patiño-Mercau, Juan Rodrigo, Sanjuan-Hidalgo, Juan, Romero, Octavio A., Montuenga, Luis M., Carretero, Julian, Sanchez-Cespedes, Montserrat, Medina, Pedro P.
Gepubliceerd in Cancers (Basel) (2020)

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

door Singh, Anju, Ruiz, Christian, Bhalla, Kavita, Haley, John A., Li, Qing Kay, Acquaah-Mensah, George, Montal, Emily, Sudini, Kuladeep R., Skoulidis, Ferdinandos, Wistuba, Ignacio I., Papadimitrakopoulou, Vassiliki, Heymach, John V., Boros, Laszlo G., Gabrielson, Edward, Carretero, Julian, Wong, Kwok-Kin, Haley, John D., Biswal, Shyam, Girnun, Geoffrey D.
Gepubliceerd in FASEB J (2018)

HIF2α cooperates with RAS to promote lung tumorigenesis in mice

door Kim, William Y., Perera, Samanthi, Zhou, Bing, Carretero, Julian, Yeh, Jen Jen, Heathcote, Samuel A., Jackson, Autumn L., Nikolinakos, Petros, Ospina, Beatriz, Naumov, George, Brandstetter, Kathleyn A., Weigman, Victor J., Zaghlul, Sara, Hayes, D. Neil, Padera, Robert F., Heymach, John V., Kung, Andrew L., Sharpless, Norman E., Kaelin, William G., Wong, Kwok-Kin
Gepubliceerd in 2009

HIF2α cooperates with RAS to promote lung tumorigenesis in mice

door Kim, William Y., Perera, Samanthi, Zhou, Bing, Carretero, Julian, Yeh, Jen Jen, Heathcote, Samuel A., Jackson, Autumn L., Nikolinakos, Petros, Ospina, Beatriz, Naumov, George N., Brandstetter, Kathleyn A., Weigman, Victor J., Zaghlul, Sara, Hayes, D. Neil, Padera, Robert F., Heymach, John V., Kung, Andrew L., Sharpless, Norman E., Kaelin, William G., Wong, Kwok-Kin
Gepubliceerd in 2009

Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene

door Chen, Zhao, Sasaki, Takaaki, Tan, Xiaohong, Carretero, Julian, Shimamura, Takeshi, Li, Danan, Xu, Chunxiao, Wang, Yuchuan, Adelmant, Guillaume O., Capelletti, Marzia, Lee, Hyun Joo, Rodig, Scott J., Borgman, Christa, Park, Seung-il, Kim, Hyeong Ryul, Padera, Robert, Marto, Jarrod A., Gray, Nathanael S., Kung, Andrew L., Shapiro, Geoffrey I., Jänne, Pasi A., Wong, Kwok-Kin
Gepubliceerd in 2010

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

door Straume, Oddbjørn, Shimamura, Takeshi, Lampa, Michael J. G., Carretero, Julian, Øyan, Anne M., Jia, Di, Borgman, Christa L., Soucheray, Margaret, Downing, Sean R., Short, Sarah M., Kang, Soo-Young, Wang, Souming, Chen, Liang, Collett, Karin, Bachmann, Ingeborg, Wong, Kwok-Kin, Shapiro, Geoffrey I., Kalland, Karl Henning, Folkman, Judah, Watnick, Randolph S., Akslen, Lars A., Naumov, George N.
Gepubliceerd in 2012

Interleukin-17A Promotes Lung Tumor Progression Through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

door Akbay, Esra A., Koyama, Shohei, Liu, Yan, Dries, Ruben, Bufe, Lauren E., Silkes, Michael, Alam, Maksudul, Magee, Dillon M., Jones, Robert, Jinushi, Masahisa, Kulkarni, Meghana, Carretero, Julian, Wang, Xiaoen, Warner-Hatten, Tiquella, Cavanaugh, Jillian D., Bufe, Lauren E., Osa, Akio, Kumanogoh, Atsushi, Freeman, Gordon J., Awad, Mark M, Christiani, David C., Bueno, Raphael, Hammerman, Peter S., Dranoff, Glenn, Wong, Kwok-Kin
Gepubliceerd in J Thorac Oncol (2017)

Targeting Transcriptional Addictions In Small Cell Lung Cancer With a Covalent CDK7 Inhibitor

door Christensen, Camilla L., Kwiatkowski, Nicholas, Abraham, Brian J., Carretero, Julian, Al-shahrour, Fatima, Zhang, Tinghu, Chipumuro, Edmond, Herter-Sprie, Grit S., Akbay, Esra A., Altabef, Abigail, Zhang, Jianming, Shimamura, Takeshi, Capelletti, Marzia, Reibel, Jakob B., Cavanaugh, Jillian, Gao, Peng, Liu, Yan, Michaelsen, Signe R., Poulsen, Hans S., Aref, Amir R., Barbie, David A., Bradner, James E., George, Rani, Gray, Nathanael S., Young, Richard A., Wong, Kwok-Kin
Gepubliceerd in Cancer Cell (2014)

Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC

door Pulido, Inés, Ollosi, Stephen, Aparisi, Salvador, Becker, Jeffrey H., Aliena-Valero, Alicia, Benet, Marta, Rodríguez, María L., López, Adrián, Tamayo-Torres, Eva, Chuliá-Peris, Lourdes, García-Cañaveras, Juan Carlos, Soucheray, Margaret, Dalheim, Annika V., Salom, Juan B., Qiu, Wei, Kaja, Simon, Fernández-Coronado, Javier Alcácer, Alandes, Sandra, Alcácer, Javier, Al-Shahrour, Fátima, Borgia, Jeffrey A., Juan, Oscar, Nishimura, Michael I., Lahoz, Agustín, Carretero, Julián, Shimamura, Takeshi
Gepubliceerd in Cancer Res (2020)