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Targeting Transcriptional Addictions In Small Cell Lung Cancer With a Covalent CDK7 Inhibitor
Small cell lung cancer (SCLC) is an aggressive disease with high mortality. The identification of effective pharmacological strategies to target SCLC biology represents an urgent need. Using a high-throughput cellular screen of a diverse chemical library we observe that SCLC is sensitive to transcri...
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| Publicado en: | Cancer Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261156/ https://ncbi.nlm.nih.gov/pubmed/25490451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.10.019 |
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