Tumor Microenvironment-Derived Metabolites: A Guide to Find New Metabolic Therapeutic Targets and Biomarkers

per García-Cañaveras, Juan C., Lahoz, Agustín
Publicat a Cancers (Basel) (2021)

CCAAT/Enhancer-binding Protein α (C/EBPα) and Hepatocyte Nuclear Factor 4α (HNF4α) Synergistically Cooperate with Constitutive Androstane Receptor to Transactivate the Human Cytoch...

per Benet, Marta, Lahoz, Agustín, Guzmán, Carla, Castell, José V., Jover, Ramiro
Publicat 2010

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

per García-Cañaveras, Juan C., Donato, M. Teresa, Castell, José V., Lahoz, Agustín
Publicat 2012

A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury

per García- Cañaveras, Juan Carlos, Castell, José V., Donato, M. Teresa, Lahoz, Agustín
Publicat a Sci Rep (2016)

Early radiological response as predictor of overall survival in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor mutations

per Salvador-Coloma, Carmen, Lorente, David, Palanca, Sarai, Simarro, Javier, Mancheño, Nuria, Sandoval, Juan, Lahoz, Agustín, Juan, Óscar
Publicat a J Thorac Dis (2018)

cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants

per Olivares-González, Lorena, Martínez-Fernández de la Cámara, Cristina, Hervás, David, Marín, María Pilar, Lahoz, Agustin, Millán, José María, Rodrigo, Regina
Publicat a PLoS One (2016)

Metabolomic Analysis of the Effect of Postnatal Hypoxia on the Retina in a Newly Born Piglet Model

per Solberg, Rønnaug, Escobar, Javier, Arduini, Alessandro, Torres-Cuevas, Isabel, Lahoz, Agustín, Sastre, Juan, Saugstad, Ola Didrik, Vento, Máximo, Kuligowski, Julia, Quintás, Guillermo
Publicat 2013

Xenobiotic metabolism in differentiated human bronchial epithelial cells

per Boei, Jan J. W. A., Vermeulen, Sylvia, Klein, Binie, Hiemstra, Pieter S., Verhoosel, Renate M., Jennen, Danyel G. J., Lahoz, Agustin, Gmuender, Hans, Vrieling, Harry
Publicat a Arch Toxicol (2016)

Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells

per Ballester, Maria, Sentandreu, Enrique, Luongo, Giovanna, Santamaria, Ramon, Bolonio, Miguel, Alcoriza-Balaguer, Maria Isabel, Palomino-Schätzlein, Martina, Pineda-Lucena, Antonio, Castell, Jose, Lahoz, Agustin, Bort, Roque
Publicat a Sci Rep (2019)

Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity

per Yildirimman, Reha, Brolén, Gabriella, Vilardell, Mireia, Eriksson, Gustav, Synnergren, Jane, Gmuender, Hans, Kamburov, Atanas, Ingelman-Sundberg, Magnus, Castell, José, Lahoz, Agustin, Kleinjans, Jos, van Delft, Joost, Björquist, Petter, Herwig, Ralf
Publicat 2011

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

per Fernández-Álvarez, Sara, Juan, Virginia Gutiérrez-de, Zubiete-Franco, Imanol, Barbier-Torres, Lucia, Lahoz, Agustín, Parés, Albert, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Mato, José M., Martínez-Chantar, María Luz, Beraza, Naiara
Publicat a Lab Invest (2014)

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

per Ghergurovich, Jonathan M., García-Cañaveras, Juan C., Wang, Joshua, Schmidt, Emily, Zhang, Zhaoyue, TeSlaa, Tara, Patel, Harshel, Chen, Li, Britt, Emily C., Piqueras-Nebot, Marta, Gomez-Cabrera, Mari Carmen, Lahoz, Agustín, Fan, Jing, Beier, Ulf H, Kim, Hahn, Rabinowitz, Joshua D.
Publicat a Nat Chem Biol (2020)

Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1

per Villalba, Maria, Redin, Esther, Exposito, Francisco, Pajares, Maria Jose, Sainz, Cristina, Hervas, David, Guruceaga, Elizabeth, Diaz-Lagares, Angel, Cirauqui, Cristina, Redrado, Miriam, Valencia, Karmele, de Andrea, Carlos, Jantus-Lewintre, Eloisa, Camps, Carlos, Lopez-Lopez, Rafael, Lahoz, Agustin, Montuenga, Luis, Pio, Ruben, Sandoval, Juan, Calvo, Alfonso
Publicat a Sci Rep (2019)

Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC

per Pulido, Inés, Ollosi, Stephen, Aparisi, Salvador, Becker, Jeffrey H., Aliena-Valero, Alicia, Benet, Marta, Rodríguez, María L., López, Adrián, Tamayo-Torres, Eva, Chuliá-Peris, Lourdes, García-Cañaveras, Juan Carlos, Soucheray, Margaret, Dalheim, Annika V., Salom, Juan B., Qiu, Wei, Kaja, Simon, Fernández-Coronado, Javier Alcácer, Alandes, Sandra, Alcácer, Javier, Al-Shahrour, Fátima, Borgia, Jeffrey A., Juan, Oscar, Nishimura, Michael I., Lahoz, Agustín, Carretero, Julián, Shimamura, Takeshi
Publicat a Cancer Res (2020)

CXCR7 reactivates ERK signaling to promote resistance to EGFR kinase inhibitors in NSCLC.

per Becker, Jeffrey H., Gao, Yandi, Soucheray, Margaret, Pulido, Ines, Kikuchi, Eiki, Rodríguez, María L., Gandhi, Rutu, Lafuente-Sanchis, Aranzazu, Aupí, Miguel, Fernández-Coronado, Javier Alcácer, Martín-Martorell, Paloma, Cremades, Antonio, Galbis-Caravajal, José M., Alcácer, Javier, Christensen, Camilla L., Simms, Patricia, Hess, Ashley, Asahina, Hajime, Kahle, Michael P., Al-Shahrour, Fatima, Borgia, Jeffrey A., Lahoz, Agustín, Insa, Amelia, Juan, Oscar, Jänne, Pasi A., Wong, Kwok-Kin, Carretero, Julian, Shimamura, Takeshi
Publicat a Cancer Res (2019)

Prediagnostic Plasma Bile Acid Levels and Colon Cancer Risk: A Prospective Study

per Kühn, Tilman, Stepien, Magdalena, López-Nogueroles, Marina, Damms-Machado, Antje, Sookthai, Disorn, Johnson, Theron, Roca, Marta, Hüsing, Anika, Maldonado, Sandra González, Cross, Amanda J, Murphy, Neil, Freisling, Heinz, Rinaldi, Sabina, Scalbert, Augustin, Fedirko, Veronika, Severi, Gianluca, Boutron-Ruault, Marie-Christine, Mancini, Francesca Romana, Sowah, Solomon A, Boeing, Heiner, Jakszyn, Paula, Sánchez, Maria J, Merino, Susana, Colorado-Yohar, Sandra, Barricarte, Aurelio, Khaw, Kay Tee, Schmidt, Julie A, Perez-Cornago, Aurora, Trichopoulou, Antonia, Karakatsani, Anna, Thriskos, Paschalis, Palli, Domenico, Agnoli, Claudia, Tumino, Rosario, Sacerdote, Carlotta, Panico, Salvatore, Bueno-de-Mesquita, Bas, van Gils, Carla H, Heath, Alicia K, Gunter, Marc J, Riboli, Elio, Lahoz, Agustín, Jenab, Mazda, Kaaks, Rudolf
Publicat a J Natl Cancer Inst (2019)