Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity

Hepatocyte-like cells derived from the differentiation of human embryonic stem cells (hES-Hep) have potential to provide a human relevant in vitro test system in which to evaluate the carcinogenic hazard of chemicals. In this study, we have investigated this potential using a panel of 15 chemicals c...

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Detalhes bibliográficos
Main Authors: Yildirimman, Reha, Brolén, Gabriella, Vilardell, Mireia, Eriksson, Gustav, Synnergren, Jane, Gmuender, Hans, Kamburov, Atanas, Ingelman-Sundberg, Magnus, Castell, José, Lahoz, Agustin, Kleinjans, Jos, van Delft, Joost, Björquist, Petter, Herwig, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Carcinogenicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216410/
https://ncbi.nlm.nih.gov/pubmed/21873647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr225
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