Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy

Por Ingelman-Sundberg, Magnus, Rodriguez-Antona, Cristina
Publicado em 2005

The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects

Por Sim, Sarah C, Ingelman-Sundberg, Magnus
Publicado em 2010

Intronic polymorphisms of cytochromes P450

Por Ingelman-Sundberg, Magnus, Sim, Sarah C
Publicado em 2010

The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

Por Lauschke, Volker M., Ingelman-Sundberg, Magnus
Publicado no Int J Mol Sci (2016)

Databases in the Area of Pharmacogenetics

Por Sim, Sarah C., Altman, Russ B., Ingelman-Sundberg, Magnus
Publicado em 2011

A novel mutant variant of the CYP2D6 gene (CYP2D6 17) common in a black African population: association with diminished debrisoquine hydroxylase activity

Por MASIMIREMBWA, COLLEN, PERSSON, IRENE, BERTILSSON, LEIF, HASLER, JULIA, INGELMAN-SUNDBERG, MAGNUS
Publicado em 1996

Hepatic Differentiation and Maturation of Human Embryonic Stem Cells Cultured in a Perfused Three-Dimensional Bioreactor

Por Sivertsson, Louise, Synnergren, Jane, Jensen, Janne, Björquist, Petter, Ingelman-Sundberg, Magnus
Publicado em 2013

In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes

Por Ivanov, Maxim, Kals, Mart, Kacevska, Marina, Metspalu, Andres, Ingelman-Sundberg, Magnus, Milani, Lili
Publicado em 2013

High CYP2A6 Enzyme Activity as Measured by a Caffeine Test and Unique Distribution of CYP2A6 Variant Alleles in Ethiopian Population

Por Aklillu, Eleni, Djordjevic, Natasa, Carrillo, Juan Antonio, Makonnen, Eyasu, Bertilsson, Leif, Ingelman-Sundberg, Magnus
Publicado em 2014

Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability

Por Hendriks, Delilah F. G., Fredriksson Puigvert, Lisa, Messner, Simon, Mortiz, Wolfgang, Ingelman-Sundberg, Magnus
Publicado no Sci Rep (2016)

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population

Por Scordo, Maria Gabriella, Aklillu, Eleni, Yasar, Umit, Dahl, Marja-Liisa, Spina, Edoardo, Ingelman-Sundberg, Magnus
Publicado em 2001

Developmental Regulation and Induction of Cytochrome P450 2W1, an Enzyme Expressed in Colon Tumors

Por Choong, Eva, Guo, Jia, Persson, Anna, Virding, Susanne, Johansson, Inger, Mkrtchian, Souren, Ingelman-Sundberg, Magnus
Publicado no PLoS One (2015)

Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers

Por Baldwin, R Michael, Ohlsson, Staffan, Pedersen, Rasmus Steen, Mwinyi, Jessica, Ingelman-Sundberg, Magnus, Eliasson, Erik, Bertilsson, Leif
Publicado em 2008

Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport

Por Ingelman-Sundberg, Magnus, Zhong, Xiao-Bo, Hankinson, Oliver, Beedanagari, Sudheer, Yu, Ai-Ming, Peng, Lai, Osawa, Yoichi
Publicado em 2013

Amidoxime Reductase System Containing Cytochrome b(5) Type B (CYB5B) and MOSC2 Is of Importance for Lipid Synthesis in Adipocyte Mitochondria

Por Neve, Etienne P. A., Nordling, Åsa, Andersson, Tommy B., Hellman, Ulf, Diczfalusy, Ulf, Johansson, Inger, Ingelman-Sundberg, Magnus
Publicado em 2012

Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas

Por Nolé, Paola, Duijndam, Britt, Stenman, Adam, Juhlin, C. Christofer, Kozyra, Mikael, Larsson, Catharina, Ingelman-Sundberg, Magnus, Johansson, Inger
Publicado no PLoS One (2016)

Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function

Por Ivanov, Maxim, Kals, Mart, Kacevska, Marina, Barragan, Isabel, Kasuga, Kie, Rane, Anders, Metspalu, Andres, Milani, Lili, Ingelman-Sundberg, Magnus
Publicado em 2013

High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis

Por Pradip, Arvind, Steel, Daniella, Jacobsson, Susanna, Holmgren, Gustav, Ingelman-Sundberg, Magnus, Sartipy, Peter, Björquist, Petter, Johansson, Inger, Edsbagge, Josefina
Publicado no Stem Cells Int (2016)

Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell–Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Sys...

Por Bell, Catherine C., Lauschke, Volker M., Vorrink, Sabine U., Palmgren, Henrik, Duffin, Rodger, Andersson, Tommy B., Ingelman-Sundberg, Magnus
Publicado no Drug Metab Dispos (2017)

Regulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth Hormone

Por Löfgren, Susanne, Baldwin, R. Michael, Carlerös, Margareta, Terelius, Ylva, Fransson-Steen, Ronny, Mwinyi, Jessica, Waxman, David J., Ingelman-Sundberg, Magnus
Publicado em 2009