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Regulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth Hormone
The hormonal regulation of human CYP2C18 and CYP2C19, which are expressed in a male-specific manner in liver and kidney in a mouse transgenic model, was examined. The influence of prepubertal castration in male mice and testosterone treatment of female mice was investigated, as was the effect of con...
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Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society for Pharmacology and Experimental Therapeutics
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698944/ https://ncbi.nlm.nih.gov/pubmed/19339376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.026963 |
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