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Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas

Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. The level of expression is higher in colon metastases than in the parent tumors and the enzyme is a possible drug target for treatment of colorectal cancer, as demonstrated in mouse xenograft studies. A previou...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Nolé, Paola, Duijndam, Britt, Stenman, Adam, Juhlin, C. Christofer, Kozyra, Mikael, Larsson, Catharina, Ingelman-Sundberg, Magnus, Johansson, Inger
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012573/
https://ncbi.nlm.nih.gov/pubmed/27598485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162379
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