Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas

Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. The level of expression is higher in colon metastases than in the parent tumors and the enzyme is a possible drug target for treatment of colorectal cancer, as demonstrated in mouse xenograft studies. A previou...

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Publicat a:PLoS One
Autors principals: Nolé, Paola, Duijndam, Britt, Stenman, Adam, Juhlin, C. Christofer, Kozyra, Mikael, Larsson, Catharina, Ingelman-Sundberg, Magnus, Johansson, Inger
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012573/
https://ncbi.nlm.nih.gov/pubmed/27598485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162379
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