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Intronic polymorphisms of cytochromes P450

The cytochrome P450 enzymes active in drug metabolism are highly polymorphic. Most allelic variants have been described for enzymes encoded by the cytochrome P450 family 2 (CYP2) gene family, which has 252 different alleles. The intronic polymorphisms in the cytochrome P450 genes account for only a...

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Détails bibliographiques
Auteurs principaux: Ingelman-Sundberg, Magnus, Sim, Sarah C
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525217/
https://ncbi.nlm.nih.gov/pubmed/20846929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-4-6-402
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