High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis

Hepatotoxicity is one of the most cited reasons for withdrawal of approved drugs from the market. The use of nonclinically relevant in vitro and in vivo testing systems contributes to the high attrition rates. Recent advances in differentiating human induced pluripotent stem cells (hiPSCs) into pure...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cells Int
Päätekijät: Pradip, Arvind, Steel, Daniella, Jacobsson, Susanna, Holmgren, Gustav, Ingelman-Sundberg, Magnus, Sartipy, Peter, Björquist, Petter, Johansson, Inger, Edsbagge, Josefina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736406/
https://ncbi.nlm.nih.gov/pubmed/26880940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2475631
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