New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis

Por Souza, Terezinha, Jennen, Danyel, van Delft, Joost, van Herwijnen, Marcel, Kyrtoupolos, Soterios, Kleinjans, Jos
Publicado no Arch Toxicol (2015)

Application of four dyes in gene expression analyses by microarrays

Por Staal, Yvonne CM, van Herwijnen, Marcel HM, van Schooten, Frederik J, van Delft, Joost HM
Publicado em 2005

An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Por Ruiz-Aracama, Ainhoa, Peijnenburg, Ad, Kleinjans, Jos, Jennen, Danyel, van Delft, Joost, Hellfrisch, Caroline, Lommen, Arjen
Publicado em 2011

Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

Por Jennen, Danyel, Ruiz-Aracama, Ainhoa, Magkoufopoulou, Christina, Peijnenburg, Ad, Lommen, Arjen, van Delft, Joost, Kleinjans, Jos
Publicado em 2011

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

Por Kleinjans Jos, van Delft Joost, Bonassi Stefano, Gmuender Hans, van Leeuwen Danitsja, Moretti Stefano, Patrone Fioravante, Merlo Domenico
Publicado em 2008-09-01

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

Por Moretti, Stefano, van Leeuwen, Danitsja, Gmuender, Hans, Bonassi, Stefano, van Delft, Joost, Kleinjans, Jos, Patrone, Fioravante, Merlo, Domenico Franco
Publicado em 2008

Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle

Por Radford, Robert, Slattery, Craig, Jennings, Paul, Blacque, Oliver, Pfaller, Walter, Gmuender, Hans, Van Delft, Joost, Ryan, Michael P., McMorrow, Tara
Publicado em 2012

Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells

Por Nymark, Penny, Alstrup, Jensen Keld, Suhonen, Satu, Kembouche, Yahia, Vippola, Minnamari, Kleinjans, Jos, Catalán, Julia, Norppa, Hannu, van Delft, Joost, Briedé, Jacob Jan
Publicado em 2014

Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach

Por Van Summeren, Anke, Renes, Johan, Lizarraga, Daneida, Bouwman, Freek G., Noben, Jean-Paul, van Delft, Joost H. M., Kleinjans, Jos C. S., Mariman, Edwin C. M.
Publicado em 2013

Transcriptome Analysis in Peripheral Blood of Humans Exposed to Environmental Carcinogens: A Promising New Biomarker in Environmental Health Studies

Por van Leeuwen, Danitsja M., Gottschalk, Ralph W.H., Schoeters, Greet, van Larebeke, Nicolas A., Nelen, Vera, Baeyens, Willy F., Kleinjans, Jos C.S., van Delft, Joost H.M.
Publicado em 2008

Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity

Por Yildirimman, Reha, Brolén, Gabriella, Vilardell, Mireia, Eriksson, Gustav, Synnergren, Jane, Gmuender, Hans, Kamburov, Atanas, Ingelman-Sundberg, Magnus, Castell, José, Lahoz, Agustin, Kleinjans, Jos, van Delft, Joost, Björquist, Petter, Herwig, Ralf
Publicado em 2011

Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes

Por Jetten, Marlon J. A., Ruiz-Aracama, Ainhoa, Coonen, Maarten L. J., Claessen, Sandra M., van Herwijnen, Marcel H. M., Lommen, Arjen, van Delft, Joost H. M., Peijnenburg, Ad A. C. M., Kleinjans, Jos C. S.
Publicado no Arch Toxicol (2015)

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

Por van Delft Joost HM, Geraedts Joep PM, Nelen Vera, Baeyens Willy F, Schoeters Greet, Koppen Gudrun, Knaapen Ad M, Gottschalk Ralph WH, Godschalk Roger WL, Ketelslegers Hans B, Kleinjans Jos CS, van Larebeke Nicolas A
Publicado em 2011-10-01

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

Por Ketelslegers, Hans B, Godschalk, Roger WL, Gottschalk, Ralph WH, Knaapen, Ad M, Koppen, Gudrun, Schoeters, Greet, Baeyens, Willy F, Nelen, Vera, Geraedts, Joep PM, van Delft, Joost HM, Kleinjans, Jos CS, van Larebeke, Nicolas A
Publicado em 2011

Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

Por Doktorova, T. Y., Yildirimman, Reha, Ceelen, Liesbeth, Vilardell, Mireia, Vanhaecke, Tamara, Vinken, Mathieu, Ates, Gamze, Heymans, Anja, Gmuender, Hans, Bort, Roque, Corvi, Raffaella, Phrakonkham, Pascal, Li, Ruoya, Mouchet, Nicolas, Chesne, Christophe, van Delft, Joost, Kleinjans, Jos, Castell, Jose, Herwig, Ralf, Rogiers, Vera
Publicado no EXCLI J (2014)

Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM–ICCVAM/NICEATM Considerations for Regulatory Use

Por Corvi, Raffaella, Ahr, Hans-Jürgen, Albertini, Silvio, Blakey, David H., Clerici, Libero, Coecke, Sandra, Douglas, George R., Gribaldo, Laura, Groten, John P., Haase, Bernd, Hamernik, Karen, Hartung, Thomas, Inoue, Tohru, Indans, Ian, Maurici, Daniela, Orphanides, George, Rembges, Diana, Sansone, Susanna-Assunta, Snape, Jason R., Toda, Eisaku, Tong, Weida, van Delft, Joost H., Weis, Brenda, Schechtman, Leonard M.
Publicado em 2006

Micronuclei in Cord Blood Lymphocytes and Associations with Biomarkers of Exposure to Carcinogens and Hormonally Active Factors, Gene Polymorphisms, and Gene Expression: The NewGen...

Por Merlo, Domenico Franco, Agramunt, Silvia, Anna, Lívia, Besselink, Harrie, Botsivali, Maria, Brady, Nigel J., Ceppi, Marcello, Chatzi, Leda, Chen, Bowang, Decordier, Ilse, Farmer, Peter B., Fleming, Sarah, Fontana, Vincenzo, Försti, Asta, Fthenou, Eleni, Gallo, Fabio, Georgiadis, Panagiotis, Gmuender, Hans, Godschalk, Roger W., Granum, Berit, Hardie, Laura J., Hemminki, Kari, Hochstenbach, Kevin, Knudsen, Lisbeth E., Kogevinas, Manolis, Kovács, Katalin, Kyrtopoulos, Soterios A., Løvik, Martinus, Nielsen, Jeanette K, Nygaard, Unni Cecilie, Pedersen, Marie, Rydberg, Per, Schoket, Bernadette, Segerbäck, Dan, Singh, Rajinder, Sunyer, Jordi, Törnqvist, Margareta, van Loveren, Henk, van Schooten, Frederik J., Vande Loock, Kim, von Stedingk, Hans, Wright, John, Kleinjans, Jos C., Kirsch-Volders, Micheline, van Delft, Joost H.M.
Publicado em 2013

A comprehensive study design reveals treatment- and transcript abundance–dependent concordance between RNA-seq and microarray data

Por Wang, Charles, Gong, Binsheng, Bushel, Pierre R., Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Xu, Joshua, Fang, Hong, Hong, Huixiao, Shen, Jie, Su, Zhenqiang, Meehan, Joe, Li, Xiaojin, Yang, Lu, Li, Haiqing, Łabaj, Paweł P., Kreil, David P., Megherbi, Dalila, Florian, Caiment, Gaj, Stan, van Delft, Joost, Kleinjans, Jos, Scherer, Andreas, Viswanath, Devanarayan, Wang, Jian, Yang, Yong, Qian, Hui-Rong, Lancashire, Lee J., Bessarabova, Marina, Nikolsky, Yuri, Furlanello, Cesare, Chierici, Marco, Albanese, Davide, Jurman, Giuseppe, Riccadonna, Samantha, Filosi, Michele, Visintainer, Roberto, Zhang, Ke K., Li, Jianying, Hsieh, Jui-Hua, Svoboda, Daniel L., Fuscoe, James C., Deng, Youping, Shi, Leming, Paules, Richard S., Auerbach, Scott S., Tong, Weida
Publicado no Nat Biotechnol (2014)