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Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle

The primary cilium is an immotile sensory and signaling organelle found on the majority of mammalian cell types. Of the multitude of roles that the primary cilium performs, perhaps some of the most important include maintenance of differentiation, quiescence, and cellular polarity. Given that the pr...

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Detalhes bibliográficos
Main Authors: Radford, Robert, Slattery, Craig, Jennings, Paul, Blacque, Oliver, Pfaller, Walter, Gmuender, Hans, Van Delft, Joost, Ryan, Michael P., McMorrow, Tara
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729533/
https://ncbi.nlm.nih.gov/pubmed/22262483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00427.2011
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