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Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle

The primary cilium is an immotile sensory and signaling organelle found on the majority of mammalian cell types. Of the multitude of roles that the primary cilium performs, perhaps some of the most important include maintenance of differentiation, quiescence, and cellular polarity. Given that the pr...

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Bibliografski detalji
Glavni autori: Radford, Robert, Slattery, Craig, Jennings, Paul, Blacque, Oliver, Pfaller, Walter, Gmuender, Hans, Van Delft, Joost, Ryan, Michael P., McMorrow, Tara
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729533/
https://ncbi.nlm.nih.gov/pubmed/22262483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00427.2011
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