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The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell. This protein is encoded by the CTNS gene which is defective in the lysosomal storage disorder, cystinosis. Because of the apparent involvement of cy...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Sumayao, Rodolfo, Newsholme, Philip, McMorrow, Tara
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315507/
https://ncbi.nlm.nih.gov/pubmed/30513914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7120179
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